Neonatal pustular eruptions are a group of disorders characterized by various forms of pustulosis (rashes consisting at least in part of pustules) seen in the first four weeks of life.[1]

This grouping can help aid in differential diagnosis.

Neonatal pustular eruptions can be further divided into noninfectious and infectious causes.

Non-infectious causes

The non-infectious causes are generally benign and self-limited.

Infectious causes

Bacteria

Most commonly these are primary cutaneous infections, caused by Staphylococcus aureus or beta-hemolytic streptococci. This would be called bullous impetigo. When more severe, these cutaneous infections would develop into furuncles (infections run deeper into the skin).

Congenital syphilis is another bacterial infection of the skin that can cause pustules in the neonatal period.

Listeriosis

Virus

Fungal

  • Congenital candidiasis - Congenital candidiasis results due to intrauterine candidal infection of fetus.
  • Neonatal candidiasis - It is perinatally acquired candidal infection, manifesting after the sixth day of life.
  • Malassezia furfur, which causes benign neonatal cephalic pustulosis, also called neonatal malasezzia furfur pustulosis.

References

  1. ↑ Ghosh, S (March 2015). "Neonatal pustular dermatosis: an overview". Indian Journal of Dermatology. 60 (2): 211. doi:10.4103/0019-5154.152558 (inactive 2023-09-24). PMC 4372928. PMID 25814724.{{cite journal}}: CS1 maint: DOI inactive as of September 2023 (link)
  2. 1 2 "Vesicular, pustular, and bullous lesions in the newborn and infant". UpToDate. Retrieved 1 September 2023.
  3. ↑ "Transient neonatal pustular melanosis". Contemporary Pediatrics. 9 (12). Dec 20, 2010.
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