KDM7A

KDM7A
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	3KV5, 3KV6, 3KV9, 3KVA, 3KVB, 3U78
Identifiers
Aliases	KDM7A, JHDM1D, lysine demethylase 7A
External IDs	MGI: 2443388 HomoloGene: 25281 GeneCards: KDM7A
Gene location (Human)
Chr.	Chromosome 7 (human)
End	140,176,983 bp
Gene location (Mouse)
Chr.	Chromosome 6 (mouse)
End	39,183,723 bp
RNA expression pattern
	Top expressed in
	bone marrow; ; monocyte; ; bone marrow cells; ; jejunal mucosa; ; spongy bone; ; gastrocnemius muscle; ; blood; ; sperm; ; pericardium; ; thymus;
	Top expressed in
	blood; ; secondary oocyte; ; left lung lobe; ; cerebellar vermis; ; trigeminal ganglion; ; soleus muscle; ; body of femur; ; intercostal muscle; ; olfactory tubercle; ; triceps brachii muscle;
	More reference expression data
	n/a
Gene ontology
Molecular function	2-oxoglutarate-dependent dioxygenase activity; iron ion binding; histone H3-methyl-lysine-9 demethylase activity; histone H4-methyl-lysine-20 demethylase activity; dioxygenase activity; metal ion binding; methylated histone binding; histone H3-methyl-lysine-36 demethylase activity; oxidoreductase activity; histone H3-tri/di-methyl-lysine-27 demethylase activity; histone demethylase activity; zinc ion binding;
Cellular component	nucleoplasm; nucleolus; nucleus;
Biological process	regulation of transcription, DNA-templated; histone H3-K27 demethylation; histone H3-K9 demethylation; histone H4-K20 demethylation; transcription, DNA-templated; nervous system development; positive regulation of transcription, DNA-templated; histone H3-K36 demethylation; midbrain development; chromatin organization;
	Sources:Amigo / QuickGO
Orthologs
	80853
	338523
	ENSG00000006459
	ENSMUSG00000042599
	Q6ZMT4
	Q3UWM4
	NM_030647
	NM_001033430
	NP_085150
	NP_001028602
	Wikidata
View/Edit Human	View/Edit Mouse

Lysine demethylase 7A is a protein that in humans is encoded by the KDM7A gene. ^[5]

References

1 2 3 GRCh38: Ensembl release 89: ENSG00000006459 - Ensembl, May 2017
1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000042599 - Ensembl, May 2017
↑ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
↑ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
↑ "Entrez Gene: Lysine demethylase 7A". Retrieved 2016-04-09.

External links

PDBe-KB provides an overview of all the structure information available in the PDB for Human Lysine-specific demethylase 7A (KDM7A)

This article is issued from Wikipedia. The text is licensed under Creative Commons - Attribution - Sharealike. Additional terms may apply for the media files.

[refGRCh38Ensembl-1] 1 2 3 GRCh38: Ensembl release 89: ENSG00000006459 - Ensembl, May 2017

[refGRCm38Ensembl-2] 1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000042599 - Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[entrez-5] "Entrez Gene: Lysine demethylase 7A". Retrieved 2016-04-09.

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References

Further reading

External links