Mary Patterson may refer to:
- Mary Patterson (politician) (1927–2016) , American singer and politician
- Mary Patterson Clark (born 1936), Canadian architect
- Mary Jane Patterson (1840– 1894), first African-American woman to receive a B.A degree
- Mary Michael Patterson, American theater actress and singer
- Mary Paterson (1864–1941), British factory inspector and philanthropist
- Mary Baker Eddy (1821–1910), American religious leader known for a short time as Mary Patterson
See also
- Mary A. Patterson Memorial, memorial to the wife of Monroe Patterson
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