The following highways are numbered 349:

Canada

• Manitoba Provincial Road 349
• Nova Scotia Route 349
• Prince Edward Island Route 349
• Quebec Route 349
• Saskatchewan Highway 349

Japan

• Japan National Route 349

United States

• Arkansas Highway 349
• Connecticut Route 349
• Florida State Road 349
  • County Road 349 (Dixie County, Florida)
• Georgia State Route 349 (former)
• Maryland Route 349
• New York:
  • New York State Route 349
  • County Route 349 (Erie County, New York)
• Ohio State Route 349
• Pennsylvania Route 349
• Puerto Rico Highway 349
• Texas:
  • Texas State Highway 349
  • Farm to Market Road 349
• Virginia State Route 349